Folding@Home

  • Thread starter Burnout
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So, anyone either already do this or is interested - If so I'd be willling to start a team and place all my folders on it.

Alright, if you haven't heard about it, this is how it works: "What are proteins and why do they "fold"? Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out their biochemical function, they remarkably assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, remains a mystery. Moreover, perhaps not surprisingly, when proteins do not fold correctly (i.e. "misfold"), there can be serious effects, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, and Parkinson's disease.

What does Folding@Home do? Folding@Home is a distributed computing project which studies protein folding, misfolding, aggregation, and related diseases. We use novel computational methods and large scale distributed computing, to simulate timescales thousands to millions of times longer than previously achieved. This has allowed us to simulate folding for the first time, and to now direct our approach to examine folding related disease."

We could start a Team GTP and fold!

If you're interested - Just tell me here. It doesn't slow down your computer at all, the thread priotity is idle, so anything else you do will have priority, in turn not slowing down your system! I do this on all my computers and have no difference in speed. It only takes a few MB in RAM, and that's it.

Any more questions or whatever - I would like to have a few people if we were to start this thing. There is also sort of a competition involved. Even though folding isn't for winning this little game deal, it keeps it interesting and kind of exciting. You get WUs for how much folding you do, which is based on how fast you completed your steps. The faster, the more WUs. There are teams with total points, single members and everything. It's pretty cool - And for good cause!

If you are interested, I'll give info on how to start.

:)
 
Sorry, bud. I don't like the extra stuff running on my pc, I like to keep her clean. I didn't go for the SETI@home or whatever it is, the alien search thing. So, I'm not doin this either, sorry.
 
That would be "tertiary structure".

*waves molecular biology degrees in the air*

For reference, CJD - or at least nvCJD, the current disease of choice - isn't caused by a mis-folded protein, but a different protein altogether taking the place of the normal PrPn protein.
 
*falls into a trance*

*snaps out*

Cool - I bet that was a fun time in school :rolleyes: (:

So, are you running a folding client? Aren't there several? I don't even know which ones are available anymore, and are there any for Mac OS X?
 
I'm running the consol version of F@H as a service so it doesn't have to stay as an open program. I run it on three machines, will be four in not too long. I'll check into the Mac thing.
 
Originally posted by Famine
That would be "tertiary structure".

*waves molecular biology degrees in the air*

For reference, CJD - or at least nvCJD, the current disease of choice - isn't caused by a mis-folded protein, but a different protein altogether taking the place of the normal PrPn protein.

Now If I need bio help I know who to PM ;)
 
Originally posted by toyomatt84
Doesn't waste space? :D
:eek:
Waste space?!
:mad:

Nerve.

So, only you even asked about it LoudMusic? Forget this - I'll stick with my current team.

For humanity's sake - You all suck!
:rolleyes:
 
Sorry, bud. But, it's not that I don't care, it's that I don't have that kind of resources to waste, well not waste, use. Anyways, my grandfather has Alzheimers, so I know it's importance.
 
Originally posted by toyomatt84
Sorry, bud. But, it's not that I don't care, it's that I don't have that kind of resources to waste, well not waste, use. Anyways, my grandfather has Alzheimers, so I know it's importance.

I was being sarcastic, I suppose tags would have helped.
 
I'm not sure how it "doesn't waste space", but whatever.

Burnout -- When I get in the top 100 overall on RC5-72 I'm going to switch over to folding (if there is an easy way to make it descrete to the user).
 
Originally posted by LoudMusic
I'm not sure how it "doesn't waste space", but whatever.

Burnout -- When I get in the top 100 overall on RC5-72 I'm going to switch over to folding (if there is an easy way to make it descrete to the user).
Yep.

Run it as a Windows service.
 
Well, in Windows, yes, but also in OS X. That's where my real horsepower is. I now have ten dual 2ghz G5 Power Macs. For referance ...

2.4GHZ P4 = 3.2 million keys / sec
2 GHZ G5 = 14.9 million keys / sec

P4 = 1.33 million keys / sec / 100mhz
G5 = 7.45 million keys / sec / 100mhz

The G5 is 5.6 times faster (at cracking RC5-72) per 100mhz than the P4. Yowza. And the G4 isn't much slower per mhz

I've calculated 40GHZ of G5, roughly 12.5GHZ of G4, and roughly 35GHZ of usable Pentium 3 and 4. What I really need to do is have it start at 7pm and run for 12 hours. That way it's not interfiering with daily use.

** All of these numbers have major fudge factor included (:
 
Originally posted by LoudMusic
Well, in Windows, yes, but also in OS X. That's where my real horsepower is. I now have ten dual 2ghz G5 Power Macs. For referance ...

2.4GHZ P4 = 3.2 million keys / sec
2 GHZ G5 = 14.9 million keys / sec

P4 = 1.33 million keys / sec / 100mhz
G5 = 7.45 million keys / sec / 100mhz

The G5 is 5.6 times faster (at cracking RC5-72) per 100mhz than the P4. Yowza. And the G4 isn't much slower per mhz

I've calculated 40GHZ of G5, roughly 12.5GHZ of G4, and roughly 35GHZ of usable Pentium 3 and 4. What I really need to do is have it start at 7pm and run for 12 hours. That way it's not interfiering with daily use.

** All of these numbers have major fudge factor included (:

Yoooo...

That would seriously send the team flying up the ranks!

Although the importaint thing is to get protiens folded!
 
Yeah. I assume Folding has been optimized for the G4 / G5, but I don't know for sure. I can look that up on their site though.
 
I know it's most likely optimized and all, but I'm trying to find the way to make it run in the background.

Not very familiar with Macs so I'll ask the nerds at the gerk forum I goto about it.
 
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