Not if you raise to a high level first... the Hunter is damn near invincible if you get a couple hundred levels of vigilante under your belt.
I got out of one once, and it -- no exaggeration -- took about 100 shoulder rockets to destroy it (direct hits).
I landed it at the Hyman Condo, and I tried to blow it up... after about 50 shots, it fell off the roof... I went downstairs and shot it about 50 more times in the middle of the street before it FINALLY blew up... and it was upside down at the time, so I think it was constantly taking damage from that too.
- bbitto