I don't know. But from the trailers it sure sounds like a remake of the 1971 classic The Omega Man starring Charlton Heston. That movie is itself based on an excellent book called I Am Legend by Richard Matheson.
Ok. Well, from the preview that I've seen. The very last scene from Resident Evil seems to be in 28 Days Later. Where the guy walks out of the hospital or something and into the empty streets?
This was a very minor British film, but it became a cult hit. And now it is being released in the US. I haven't seen it but loads of people are raving about it.