Aspyrin

[Famine]

I Think there is Salycic Acid in my contact cleaning solution

Also, In hearf that if you take aspirin before you turn 18 (might be 21) that you will get a Brain tumor... Is this true?

Why would it be?

What magical biological change occurs at 18 that would suddenly prevent this brain tumour?


Paracetamol damages the liver. In the normal course of events, this damage is repaired. In the event of an paracetamol overdose, even if the stomach is pumped, the levels of paracetamol absorbed into the blood can lead to irrevocable liver damage. Many ODers of paracetamol who change their minds subsequently die of liver failure before a donor lobe can be found.

Edit: Aspirin Toxicity Information:
Aspirin should not be given to children with a fever, as it can cause "Reye's Disease"
The toxic level for Aspirin in adults is roughly 60mg/kg/day.

 

[Will.c]

It's funny how so many things which are intended to cure people can also be lethal..

 

[Iceman]

That can be associated with almost any food or product. Of course if you eat a whole bottle of aspirin something will happen to you.

 

[PublicSecrecy]

Ok, i'm still warry of this: Can you really OD on oxygen? I dont think you could, because if you started breathing really fast you would just hyperventilate and then NOT get enough oxygen and then pass out...and if you took really long slow breath's you'd be fine...seems like the term contradicts itself.

*Edit: Myabe im not thinking out-of-the-box enough. By this could you overdose by having too much oxygen in your blood or in your brain or something? If anything i think it would be CO2 we should be concerned about in our blood.

 

[Famine]

Ok, i'm still warry of this: Can you really OD on oxygen? I dont think you could, because if you started breathing really fast you would just hyperventilate and then NOT get enough oxygen and then pass out...and if you took really long slow breath's you'd be fine...seems like the term contradicts itself.

*Edit: Myabe im not thinking out-of-the-box enough. By this could you overdose by having too much oxygen in your blood or in your brain or something? If anything i think it would be CO2 we should be concerned about in our blood.

Pure oxygen can be lethal, yes. "Breathing really fast" would have no effect, as you're still taking in 21% oxygen, 78% nitrogen and 1% "other" (including argon, neon, krypton, radon & carbon dioxide). Breathing in 100% oxygen is a different matter.

It would lead to "hyperoxia" and, although I'd have to look this up, you'd effectively have carbolic acid floating around in your blood stream.

Oh, not to mention the fact that you'd be highly, highly flammable.


Air containing less than 15% oxygen will cause sever drowsiness. Air containing less than 10% oxygen will cause unconsciousness. Air containing less than 5% oxygen will lead to death - inside ONE breath.

 

[ExigeEvan]

Edit: Aspirin Toxicity Information:
Aspirin should not be given to children with a fever, as it can cause "Reye's Disease"
The toxic level for Aspirin in adults is roughly 60mg/kg/day.

I found that out this morning when I took 1 (yes, just 1) aspirin.

You can die due to breathing really fast can't you? Or at least hyperventilating. Isn't it because you get so much oxygen into your system your body loses the reflex to breath.

A girl in my school (typical drama queen) tried to commit suicide on 12 paracetomol. We all just laughed at her. perhaps we shouldn't have
To find out what this girl looks like, search "alecsandra manning rees" on google images!

 

[Div is back]

So if I take 60mg of aspirin I'll pass out? or die?

60 mg = X pills?

x = ?

 

[Raptor65]

It would lead to "hyperoxia" and, although I'd have to look this up, you'd effectively have carbolic acid floating around in your blood stream.

Dorlands Medical Dictionary-Hyperoxia (see oxygen toxicity, under toxicity)- The effects of hyperoxia due to the breathing of high partial pressures of oxygen for prolonged periods; they include serious, sometimes irreversible, damge to the pulmonary capillary endothelium, followed by cerebral edema and convulsions that can be fatal, also called oxygen poisoning.

Also, I looked up Carbolic Acid (i'd never heard of it) and it referred me to phenol (1st definition) and it said "an extremely poisonous, colorless to light pink, crystallin compound, C6H5OH, obtained by the distillation of coal tar....Called also Carbolic Acid." Why would carbolic acid be floating around the blood stream? I'm just curious and I love learning about stuff like this so please explain.

 

[Famine]

Dorlands Medical Dictionary-Hyperoxia (see oxygen toxicity, under toxicity)- The effects of hyperoxia due to the breathing of high partial pressures of oxygen for prolonged periods; they include serious, sometimes irreversible, damge to the pulmonary capillary endothelium, followed by cerebral edema and convulsions that can be fatal, also called oxygen poisoning.

Also, I looked up Carbolic Acid (i'd never heard of it) and it referred me to phenol (1st definition) and it said "an extremely poisonous, colorless to light pink, crystallin compound, C6H5OH, obtained by the distillation of coal tar....Called also Carbolic Acid." Why would carbolic acid be floating around the blood stream? I'm just curious and I love learning about stuff like this so please explain.

It's just possible I meant Carbonic Acid.

It's part of the carbon dioxide transport pathway, but I'm 250 miles from my Molecular Biology textbooks, so can't check properly.

So if I take 60mg of aspirin I'll pass out? or die?

60 mg = X pills?

x = ?

If you weighed 1kg, yes.

It's 60mg/kg/day. That's 60mg per kg bodyweight per day.

One tablet typically contains 300mg of aspirin.

 

[Raptor65]

It's just possible I meant Carbonic Acid.

It's part of the carbon dioxide transport pathway, but I'm 250 miles from my Molecular Biology textbooks, so can't check properly.


Yeah, Carbonic acid sounds a bit more like it. Heh, the definition was a little above my head but it did mention it being in the blood.

BTW- I think I read somewhere a while back what your profession was but i can't remeber now, so if you could refresh my memory I'd like to know. Just curious.

 

[PublicSecrecy]

About the hyperventilating thing...no you dont get too much, you get too little, when you hyperventilate you dont hold your breath in long enough for the lungs to absorb the oxygen, thus starving your brain and the rest of your body of it and then u pass out. or get dizzy. same when u drink 3 litres of coke and then jump on ur bed and let out a +10 seconds burp. I passed out. best time of my life.
As for the...carbonic acid? Is this produced by breathing in 100% oxygen, and then it begins to form in your bloodstream? Also, do you know the limits of what percentage per cubic unit of air we can safely breath in? (ie. 50% oxygen / 5parts oxygen 1 part other and 2 parts nitrogen/co2 etc. ) And, is there anything that humans cant, meaning impossible, overdose on? Anything at all? Im thinking light. i dont think you can overdose on light. Although in sunlight your body produces Vitamin D, which could eventually lead to a Vitamin D overdose...however, im pretty sure ur body would use it up pretty much in proportion to how much it produces for it to ever be harmfull unless one is taking a supplement of some sort. God i cant believe we're tlaking about this.

 

[Famine]

Too much light and you go blind. Too high energy light and your skin would, effectively, melt.

Too much of ANYTHING is bad for us. Life is a balancing act of extremes.

Carbonic acid (still need to check on it precisely) is a natural part of the carbon dioxide transport pathway from carboxyhaemoglobin to the exhaled gas. Its formation - and destruction - is normal.

Raptor - Currently I'm a science technician. I have degrees in molecular biology and human genetics.

 

[Raptor65]

About the hyperventilating thing...no you dont get too much, you get too little, when you hyperventilate you dont hold your breath in long enough for the lungs to absorb the oxygen, thus starving your brain and the rest of your body of it and then u pass out. or get dizzy. same when u drink 3 litres of coke and then jump on ur bed and let out a +10 seconds burp. I passed out. best time of my life.
As for the...carbonic acid? Is this produced by breathing in 100% oxygen, and then it begins to form in your bloodstream? Also, do you know the limits of what percentage per cubic unit of air we can safely breath in? (ie. 50% oxygen / 5parts oxygen 1 part other and 2 parts nitrogen/co2 etc. ) And, is there anything that humans cant, meaning impossible, overdose on? Anything at all? Im thinking light. i dont think you can overdose on light. Although in sunlight your body produces Vitamin D, which could eventually lead to a Vitamin D overdose...however, im pretty sure ur body would use it up pretty much in proportion to how much it produces for it to ever be harmfull unless one is taking a supplement of some sort. God i cant believe we're tlaking about this.

A simple answer and a very common occurance due to an "overdose" of light is sunburn. Too much sun=ouchies. You won't die but i guess it technically is an overdose.

BTW Famine- What exactly does a science technician do? And those are some kick-ass degrees. I bet it's nice to throw those out once in a while. *snobby British voice* "Hmmmm, Yes, I have degrees in Molecular Biology and Human Genetics." (not that i'm calling you a snob or anything).

 

[daan]

*snobby British voice* "Hmmmm, Yes, I have degrees in Molecular Biology and Human Genetics." (not that i'm calling you a snob or anything).

You've got 'im down to a T with his "posh" voice



EDIT: Although he wouldn't say it, that's how he would say it if he were to say it

 

[Div is back]

So do you actually pass out by doing an overdose of aspirin?

 

[donbenni]

Oh for Gods sake, just take an overdose and find out.






I don't really want you to take an overdose.

 

[Carlos_23]

Hmm, hello all.. interesting discussion...
I read about oxygen and the possible effects on the human body, and yes, that is the main reason we age. Also, too much oxygen can damage/destroy inner organs, especially in premature babies. By the way, does anyone know what PO2 is, exactly? I found a note on some old medical records, and I was wondering what it was...

 

[PublicSecrecy]

Too much sun= sunburn. Sun isnt light. Light is energy. Sun = giant ball of flaming nitrogen floating around in space releasing radioactive energy. Light=brightness... If i were to close my eyes however/have something protecting them, i think the body (aside from going blind) would be fine with an extremely bright light constantly aimed at it...unless it was hot or was releasing some kind of bad energy like gamma rays.

 

[skip0110]

Sun = giant ball of flaming nitrogen floating around in space releasing radioactive energy.

Nah, the sun is hydrogen and helium (I think).

 

[PublicSecrecy]

Helium isnt flammable, its a "noble gas". My point was tho, that the sun is releasing much more than just light (heat as well in case you havent noticed). I think pure light would do nothing but blind u, but that can easily be fixed by turning away or covering your eyes. I wonder if anyone has ever tested this stuff before..."hmm i wonder if i can die from too much O2" "i wonder if i can die from too much light" "i wonder if i can die from aspiryn...ill go check brb".

 

[skip0110]

The sun isn't "burning" in the classic sense, where oxygen is involved. It's powered by nuclear fission--the combining of smaller atoms' nuclei to make bigger ones.

But light (as it comes form the sun) consists of visible and invisible E/M radiation. The invisible will definitely hurt you, as it is what causes skin cancer etc (ie UV rays).

EDIT: As a general rule, I think too much of anything will kill you. Or at least not be good. (Except maybe sex )

 

[Famine]

Hmm, hello all.. interesting discussion...
I read about oxygen and the possible effects on the human body, and yes, that is the main reason we age. Also, too much oxygen can damage/destroy inner organs, especially in premature babies. By the way, does anyone know what PO2 is, exactly? I found a note on some old medical records, and I was wondering what it was...

Phosphorus dioxide.

The main reason we age is the telomeres on our chromosomes - the molecular clock. These get shorter each time the cell divides until they disappear and the chromosome start to break down. Immortalised cancer cells have an enzyme called "telomerase" which catalyses the reconstruction of telomeres, preserving their wacky, mutated chromosomes for life.

 

[Carlos_23]

Phosphorus dioxide.

The main reason we age is the telomeres on our chromosomes - the molecular clock. These get shorter each time the cell divides until they disappear and the chromosome start to break down. Immortalised cancer cells have an enzyme called "telomerase" which catalyses the reconstruction of telomeres, preserving their wacky, mutated chromosomes for life.

Great explanation. Oops, actually, I think I made one mistake, (well, two, but you've corrected one, thanks) It was p02 (Partial Oxygen Pressure), not P02 (phosphorus dioxide). What I wanted to know is, what is the correct (or normal) level of oxygen in the blood, and what can an excess pO2 level do? In my case, I know what it did, but I wanted to know more about it...
In the records I was reading, I found this: (translated from Spanish)
"...a pO2 level of 167.8 which was immediately corrected to 76.8..."
If I understand correctly, the normal level is 76.8 or something around it, and it seems someone made a huge mistake if the level was 167.8...

 

[Raptor65]

Phosphorus dioxide.

The main reason we age is the telomeres on our chromosomes - the molecular clock. These get shorter each time the cell divides until they disappear and the chromosome start to break down. Immortalised cancer cells have an enzyme called "telomerase" which catalyses the reconstruction of telomeres, preserving their wacky, mutated chromosomes for life.

When does this start to happen? At what age? How long until the chromosome breaks down? If the chromosome was breaking down, wouldn't we be losing genes, making each cell produced afterwards more and more degenerate/less able to function? What happens to a cell/the body when a chromosome breaks down?

(I hope you don't mind my questions. )

 

[Famine]

Telomeres start degrading in the 8-cell blastocyst embryonic state. So about 9 months BEFORE you're born.

And yes, you're right. As the chromosomes break down the cells become less able to function so they either apoptose (set themselves to self destruct), necrotise (die as a result of loss of function) or mutate. If a tumour suppressor gene drops off or is disabled, the cell can become cancerous (although it's a long pathway). But, for the most part, the cell just dies - in fact the whole body is a balancing act between apoptosis (programmed cell death) and proliferation.

 

[Raptor65]

Telomeres start degrading in the 8-cell blastocyst embryonic state. So about 9 months BEFORE you're born.

And yes, you're right. As the chromosomes break down the cells become less able to function so they either apoptose (set themselves to self destruct), necrotise (die as a result of loss of function) or mutate. If a tumour suppressor gene drops off or is disabled, the cell can become cancerous (although it's a long pathway). But, for the most part, the cell just dies - in fact the whole body is a balancing act between apoptosis (programmed cell death) and proliferation.

Wow, so, as soon as you're conceived you begin to die! So I guess, just like everything else in your body, the telomeres are programmed to degrade at a certain rate, and that rate differs from person to person. That's why we all don't die at the same age. Can the rate of telomere breakdown be influenced by outside action, such as drinking, smoking, or other things like that?

 

[Famine]

Yes - anything which damages a cell or its DNA, anything which influences rapid or reduced rate of proliferation will affect the lifespan of that cell.

You should also note that the rate of telomere deterioration is different in almost every type of cell. Cells which proliferate extremely rapidly (like in your nuts) need a low rate of telomere loss - which can make the dangerous if they mutate (rapid proliferation, very low rate of decay, mutant cell = cancer. Like in your nuts).

 

[Rue]

Now your just making it up!

 

[zoxxy]

Too much of ANYTHING is bad for us.

Even GT40's ?

 

[Tacet_Blue]

The sun isn't "burning" in the classic sense, where oxygen is involved. It's powered by nuclear fission--the combining of smaller atoms' nuclei to make bigger ones.

fusion... Hydrogen is converted into Helium inside the Sun

fission = nuclear bombs
fusion = holy grail of energy sources

Is aspyrin(sp?) really lethal? I've heard stories about it that it can be deadly if you take too much, or if you mix it with coke.

How much would it take for it to be lethal? with and without Coke?

This dates back to the time when there actually was cocaine in Coca Cola (and Doctor Peppers) I think it was removed in the 1930's and replaced by caffeine. The aspirin used to amplify the effects of the cocaine (cue Famine for a more accurate explanation )