In real life, race drivers usually pick either side of the road (@ La Sarthe) and not the middle since being in the centre lane would scrape the underside of the cars which can prove disastrous for a 24 hour race. In the game, this doesn't apply. What you need to be concern is how you should approach the turns and chicanes. As always start from the outside as you enter the turn and aim for the apex.
The best guide to driving on Circuit de la Sarthe is via Allan McNish (with an accompanying onboard video of Audi R10):
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