Tire pressure is, IMO the foundation for all other suspension tuning. If your pressures aren't right, the rest of the car will never be perfect. The tire of course, is the only part of the car that touches the road.
The plot for tire pressure over mechanical grip is vaguely shaped like a bell curve. Meaning it gradually goes up, then comes back down. Actually it looks more like a lopsided muffin, but moving on...
That means at too low pressures, the tire will deform under load and you won't achieve maximum grip. You may have good initial grip because at first, contact patch is larger, but as you transfer weight onto the tire, the sidewall collapses and the shape quickly changes to a far less useful one. The result is sloppy handling and non progressive/unpredictable breakaway.
Ever see someone at the track draw lines with chalk or shoe polish on their tires? They are making sure their sidewalls aren't rolling over. If the markings start to disappear as the day goes on, they know they need to increase the pressure.
But at too high pressures, the tire will bow out and reduce the size of your contact patch. This is somewhat oversimplifying, but imagine the tire standing on its tip-toes. Not enough surface area to interface with the road. The result is sharp handling, but reduced grip.
So adjusting tire pressure is like finding the best bed for Goldilocks. Not too high, not too low.
Two important things too keep in mind as you search for the golden combination.
#1- In real life, tire temps directly affect pressure. As air heats up, it will expand. So as your tires get hotter, the air pressure will increase. S2U models tire temperature, but
I don't know if the simulation actually adjusts pressure accordingly. It wouldn't surprise me if it did, though.
#2- The correct tire pressure is partly determined by how much weight the tire has on it. Put very generally and simply, the heavier a car is, the more tire pressure is generally needed to maintain the correct contact patch --
all else being equal (such as tire size).
My 3,950 lb. Audi S4 runs a street tire pressure of 38 PSI and an eye watering 44 PSI at the track (in fact, I have to buy special 'XL' or 'extra load' tires for it). Whereas my 3,250 lb. BMW Z4 M only needed 32 PSI for street driving and 36 for autocross.
This is further complicated by several factors, not the least of which is different tires like different pressures and different suspensions like different tires and so on. But I would guess S2U uses a monolithic tire model for each tire catagory, so you won't have to worry if Kumhos like 40 PSI while a Toyo likes 42 PSI like in real life. In S2U, a street tire is a street tire. And a slick is a slick.
As far as I know. I could be dead wrong.
Furthermore, in S2U, we have cars with aero downforce, which effectively makes the car heavier at high speeds... Which you can change based on how much wing you add....
Everyone got MEGO (My Eyes Glaze Over) yet?
In closing, I'll say my personal preference is not to tune tire pressure to adjust car balance (ie, oversteer or understeer) In my opinion, you are just making one end of the car worse than the other when you do that. Adjust tire pressure for max grip and use sway bars or spring rates to trim your car's balance if you really need to.
Hope that helps.
M