Originally posted by Tom McDonnell
Quincinx is nice, but it's not the best. It's just a shortcut method that yields decent results without taking quite a perfomance hit. 4x FSAA is the best of the bunch. I went through a ton of Tests a while back comparing screen shots of Return to castle Wolfenstien and in all honesty the absolute best is running a game of 1600x1200 or better. The higher resolution looks way better than the antialiasing, and keeps the level of detail sharp.
f you can run FSAA on 1600x1200 resolution then 4x is the king. It's one of those things you really need to decide for yourself whether you like better or not.
I always go for a lower resolution like 1024x768 so I can have a really high framerate which vastly improves gameplay, especially in multiplayer.