It never said that they died, just that "Due to a car crash, you lose your 2 best players for the rest of the game." They may just have been really badly injured...You mean there was a game where they had two of your players die in a car crash? That is delightful.
A little investigation found it's from Hoyle Puzzles and board games 2009. No idea what kind of game that is though.
Edit:
The actual game being played is possibly kakuro.
MediEvil?
It looks like that Vintage Habbo Hotel/Sim-esque game someone posted some months ago.
Commandos 2?
We have a winner. Saving Private Smith mission.