Exactly what happened to me. Suarez was by far the Golden Boot winner, even at the January transfer window, and I jokingly offered to sell him to Bayern for $98,000,000, which they then accepted, and I offered somebody $20,000,000 for Reina, which they accepted.
With that money, I bought a GK(Carasso from Bordeaux), and played Sterling up front with somebody I don't remember until I bought Neymar, which you should do quickly, because his value goes way up. I recommend buying Coutinho and Nani, and you might be able to buy Lloris and get about 8 years out of him.
Shelvey also turns out to be a star, got him at an 85 rating, and Sterling is also up to an 88 rating with 99 acceleration and 98 sprint speed.
I recommend you pick these players up at some point;
Hazard
Neymar
El Shaarawy
Nani(Sooner is better with him)
The entire Borussia Dortmund team

, but mainly Gotze and Reus.
Agger and Skrtel will both serve you well up until 2017, then let them retire or transfer them and play Wisdom. Wisdom should play a lot anyways because Agger gets hurt a lot. Jose Enrique is the same, but doesn't get hurt much. You can play him at LM or LB, or just sign Bale if you want.