These comments are hilarious. Why try to make scientific arguments when you clearly have no idea what you're talking about? Without using any big words, engineering/thermodynamic principles let's think about it logically...
Spin your arms around at 100rpm. Not bad, a little effort but not too bad.
Now hold 50 lb weights in your hands, spin your arms at 100 rpm. By your logic, it should take the same amount of work... I sincerely hope that common sense would tell you this is not true.
Indeed.
Look at a more direct analogy. How much throttle does it take to keep your car redlined in neutral? 10%? How much does it take in fourth gear? 100%+?
The gearbox puts load on the engine. It takes more power, and thus more fuel to keep your RPMs up the higher the gear you're in.
(What I want to know is, does the F10 have a much larger fuel tank than the F2007?)