Ok, I don't think I'd want to be completely indestructible. But if someone's offering me a Dracula type situation where I can die, but only in a very specific way (but without the need to drink the blood of the living of course), I could get on board with that.
If things start to get ugly, I'll end it myself. At least death will be on my own terms.
Until things get ugly, I'll just enjoy life for a really loooong time. You'd really be able to amass some serious knowledge in that amount of time... and money. Can you imagine never having to retire? Constantly building up cash and benefiting from 100s of years of compounding interest???
You'd be filthy rich after the first 200 years for sure.
(just crunched the numbers: $10,000 put in the market at year 1 with a 6% return means over $3 million after 100 years. After 200 years it's $1,086,093,433)
It would suck that I'd outlive my wife... and children... and their children... But I don't think that would be reason enough to not take the immortality option. Unless you're willing to commit suicide after your loved ones are gone, immortality should still be a viable option. And if you ARE willing to commit suicide, I'd presume that you're able to. So either way, immortality isn't holding you back - it's just offering you persistent youth throughout the length of life that you choose to live.
It's actually a no-brainer.